The old saying, “You are what you eat,” takes on deeper meaning when exploring the importance of gut microbiome for physical and mental health. The gut-brain axis refers to the complex, bidirectional communication between the gastrointestinal (GI) tract and the central nervous system (CNS). However, the gut-brain-axis goes beyond signaling gut sensations like hunger or fullness. The communication with the gut microbiome also involves the neuroendocrine and neuroimmune systems, the hypothalamic-pituitary-adrenal (HPA) axis, autonomic nervous system, and the vagus nerve.
Gut bacteria and hormones regulate appetite and metabolism, while neurotransmitters produced in the gut—such as serotonin and dopamine—affect mood, cognition and sleep. Microbiotas create metabolites that influence memory and behavior, while mental stress and an overactive HPA axis can disrupt gut function and spark inflammation.
When the gut microbiome is disturbed, it may contribute to conditions such as irritable bowel syndrome, anxiety, depression, autism spectrum disorder, Parkinson’s and Alzheimer’s disease. Supporting gut health through whole foods, regular exercise, mindfulness, trauma healing, adequate sleep and probiotics strengthens overall well-being.
Manja H. Podratz, DNM, Ph.D., is the founder of MANYA Whole Health and Yoga at 109 Upham St. in Mobile. For more information, call 251-234-4771 or visit DrManjaPodratz.com.
